Celta Vigo put their 7 match unbeaten run on the line awat at Bilbao.
Newly crowned champions Juve host relegation strugglers Carpi.
Swansea have kept a clean sheet in their last 3 home matches but will be tested by Sturridge & Co.
It's second versus third at Sandy Park in the best game of the weekend.
Can Leicester win at Old Trafford and become Premier League Champions?
Sevilla have failed to win any of their last 17 away league matches.
City warm up for their second leg against Real Madrid with a trip to St Mary's.
Both sides are in dire form and need a win to keep their survival hopes alive.
Valencia recent good form will be tested by top 4 hopefuls Villareal.
Inter travel to Rome looking to keep their Europa League hopes alive.